产品货号：
Z28248
中文名称：
TOP2B抗体
英文名称：
Anti-TOP2B antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TOP2B antibody |
| 指标别名 | DNA topoisomerase 2 beta;TOP2B;top2beta;TOPIIB |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,ICC/IF,IP,ELISA |
| 基因名称 | TOP2B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Peptide |
| 实际分子量 | 183kDa |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | This gene encodes a DNA topoisomerase,an enzyme that controls and alters the topologic states of DNA during transcription.This nuclear enzyme is involved in processes such as chromosome condensation,chromatid separation,and the relief of torsional stress that occurs during DNA transcription and replication.It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another,thus altering the topology of DNA.Two forms of this enzyme exist as likely products of a gene duplication event.The gene encoding this form,beta,is localized to chromosome 3 and the alpha form is localized to chromosome 17.The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance.Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.Alternative splicing results in multiple transcript variants. |
| Uniprot ID | Q02880 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | DNA topoisomerase II beta |
| 蛋白名全称 | DNA topoisomerase 2-beta |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 ImmunoPrecipitation (IP) 1:50 Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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